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Computational Biologist

Biologists
Description
Apply computational and statistical methods to study biological systems, modeling the origin, relationships, development, anatomy, and functions of organisms using large-scale data.
  • • Collaborate with experimental scientists, clinicians, and agencies to design studies and share data, tools, and findings.
  • • Program and maintain pipelines to store, process, and analyze high-throughput biological data using HPC or cloud platforms.
  • • Curate, integrate, and analyze multi-omic, phenotypic, and environmental datasets to study organismal relationships.
  • • Build statistical and machine learning models to infer gene function, pathways, and regulatory networks.
  • • Communicate results and data products to collaborators, stakeholders, and, when needed, regulatory bodies and the public.
  • • Identify, annotate, and classify genes, genomes, species, and pathways using computational methods.
  • • Present research at scientific conferences and publish in peer-reviewed venues.
  • • Plan and manage computational biology research projects, budgets, timelines, and collaborations.
  • • Model environmental and land-use effects on populations or ecosystems using remote sensing and sensor data.
  • • Integrate and analyze environmental sensor streams (e.g., salinity, pH, light, oxygen) with biological observations.
  • • Teach, mentor, and supervise students and trainees in computational methods and reproducible research.
  • • Lead and mentor bioinformatics analysts, data engineers, and research staff.
  • • Develop mechanistic and data-driven models to explore fundamental biological principles and system dynamics.
  • • Build population genomic and ecological models to support wildlife or resource management decisions.
  • • Prepare statements of work and requests for proposals for data generation, software, or analysis services.
  • • Develop decision-support tools and dashboards for renewable resource and conservation planning.
  • • Design sampling strategies and data collection protocols; specify metadata and quality control requirements.
  • • Develop and validate algorithms and risk models for disease vectors, pests, or invasive species.
  • • Prepare technical reports and reproducible analyses; produce documentation and visualizations for diverse audiences.
  • • Review proposals, analyses, and reports for methodological rigor, data integrity, and compliance with policies and standards.
  • • Write grant proposals to secure funding for computational biology research and infrastructure.
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Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
Sources & Standards: This site includes information from O*NET by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. Career Clutch has modified some of this information for student readability. USDOL/ETA has not approved, endorsed, or tested these modifications. O*NET® is a trademark of USDOL/ETA.
Last reviewed: Jan 2026
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