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Pathology Laboratory Technologist

Medical and Clinical Laboratory Technologists
Description
Perform anatomic pathology laboratory procedures to support diagnosis, prognosis, and treatment. Prepare, process, stain, and manage tissue and cytology specimens; ensure quality, safety, and regulatory compliance; may train or supervise staff.
  • • Accession, label, and track surgical, biopsy, cytology, and autopsy specimens in the LIS.
  • • Assist with gross examination by preparing cassettes, inking margins, and documenting specimens per protocols.
  • • Fix, process, and embed tissue using automated processors and paraffin embedding stations.
  • • Perform microtomy to cut and mount paraffin sections at prescribed thickness.
  • • Prepare cryostat frozen sections and slides for rapid intraoperative consultation.
  • • Stain slides using H&E, special stains, and immunohistochemistry; operate and maintain stainers and IHC platforms.
  • • Coverslip, label, and deliver slides; ensure slide quality and integrity.
  • • Prepare cytology specimens, including Pap and non-gynecologic fluids, using ThinPrep/SurePath and cell block techniques.
  • • Perform reagent preparation, lot acceptance, and daily quality control for stains and antibodies.
  • • Calibrate, operate, and maintain histology, cytology, cryostat, microtomy, and digital pathology equipment; document maintenance.
  • • Scan slides and manage digital images for telepathology and image analysis as required.
  • • Enter test orders and results in the LIS; communicate specimen status and technical findings to pathologists.
  • • Follow biosafety and exposure control practices; handle formalin and other hazardous chemicals safely.
  • • Participate in method validation, troubleshooting, and procedure revisions to optimize workflow and results.
  • • Train, mentor, or oversee laboratory assistants and technicians; support compliance with CAP, CLIA, and HIPAA standards.
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Healthcare & Human Services View
Source
Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
Sources & Standards: This site includes information from O*NET by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. Career Clutch has modified some of this information for student readability. USDOL/ETA has not approved, endorsed, or tested these modifications. O*NET® is a trademark of USDOL/ETA.
Last reviewed: Jan 2026
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