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Description
Perform complex immunohematology testing, compatibility workups, and blood component management to ensure safe transfusion therapy; may train or supervise staff.
  • • Perform ABO/Rh typing, antibody screens, and serologic or electronic crossmatches for compatibility.
  • • Analyze serologic findings and resolve ABO/Rh discrepancies, positive DATs, and complex antibody patterns.
  • • Identify and titrate unexpected antibodies; perform antigen typing or phenotyping on patient and donor samples.
  • • Conduct compatibility testing and select appropriate products for routine and special transfusion needs.
  • • Process, label, and prepare blood components, including irradiated, washed, or volume-reduced units.
  • • Receive, store, monitor, and rotate blood products to maintain inventory and traceability.
  • • Issue and document blood components according to policies, regulations, and patient requirements.
  • • Investigate suspected transfusion reactions and document, report, and communicate findings.
  • • Operate, calibrate, and maintain blood bank analyzers, centrifuges, refrigerators, freezers, and temperature monitors.
  • • Perform daily quality control, reagent QC, and equipment checks; troubleshoot out-of-range results.
  • • Prepare, validate, and manage antisera, reagents, and cells; maintain lot and QC records.
  • • Enter, verify, and release results and product data in the LIS or blood bank software.
  • • Provide technical guidance to physicians and nurses on test results and product selection.
  • • Train, assess, and supervise blood bank staff, students, or technicians as assigned.
  • • Develop, standardize, and validate procedures; ensure compliance with AABB, CAP, CLIA, and FDA requirements.
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Source
Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
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Last reviewed: Jan 2026
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