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Description
Perform complex clinical chemistry testing on body fluids to aid diagnosis, treatment, and disease prevention. Operate and maintain chemistry analyzers, validate and report results, ensure QC/QA and regulatory compliance, and may train or supervise staff.
  • • Analyze chemistry results for accuracy, precision, and clinical correlation.
  • • Conduct quantitative and qualitative analyses of blood, urine, cerebrospinal fluid, and other specimens for metabolites, enzymes, proteins, and electrolytes.
  • • Operate, calibrate, and maintain clinical chemistry analyzers, spectrophotometers, immunoassay platforms, and LC-MS/MS instruments.
  • • Prepare and verify reagents, calibrators, and quality control materials.
  • • Review and interpret daily QC; investigate shifts or trends and implement corrective actions.
  • • Enter, verify, and release results in the LIS with appropriate comments or reflex orders.
  • • Develop, validate, or optimize chemistry methods and reference intervals under established protocols.
  • • Assess specimen integrity; process, centrifuge, and aliquot samples per test requirements.
  • • Troubleshoot assay and instrument issues; coordinate service when needed.
  • • Provide technical consultation to clinicians and laboratory staff on test selection and interpretation.
  • • Maintain preventive maintenance schedules and documentation for instruments.
  • • Ensure compliance with CAP/CLIA standards, safety policies, and infection control.
  • • Perform toxicology screens, therapeutic drug monitoring, and endocrine or cardiac marker assays.
  • • Participate in proficiency testing and continuous improvement initiatives to meet turnaround and quality goals.
  • • Manage inventory and proper storage of reagents, controls, and consumables.
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Source
Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
Sources & Standards: This site includes information from O*NET by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. Career Clutch has modified some of this information for student readability. USDOL/ETA has not approved, endorsed, or tested these modifications. O*NET® is a trademark of USDOL/ETA.
Last reviewed: Jan 2026
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