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Description
Perform complex hematology and coagulation testing on blood and bone marrow to support diagnosis, treatment, and monitoring of hematologic and bleeding disorders; ensure quality results, maintain instruments, and may train or supervise staff.
  • • Perform complete blood counts, differentials, reticulocyte counts, and ESR using analyzers and microscopy.
  • • Review and verify results for accuracy, delta checks, instrument flags, and clinical plausibility.
  • • Prepare, stain, and evaluate peripheral blood and bone marrow smears; assess cell morphology and document critical findings.
  • • Conduct coagulation testing such as PT/INR, aPTT, fibrinogen, D-dimer, and mixing studies; interpret QC results.
  • • Operate, calibrate, and maintain hematology analyzers, coagulation instruments, slide stainers, and microscopes.
  • • Enter, validate, and release results in the LIS; ensure complete and accurate documentation.
  • • Perform hemoglobinopathy testing such as hemoglobin electrophoresis or HPLC and sickle cell screening.
  • • Perform and assist with flow cytometric immunophenotyping for hematologic disorders, where applicable.
  • • Implement and monitor quality control, proficiency testing, and quality assurance activities.
  • • Develop, validate, and update hematology and coagulation procedures and reference ranges.
  • • Troubleshoot instrument issues, reagent problems, sample integrity, and discrepant results; initiate corrective actions.
  • • Communicate critical values and provide technical consultation to clinicians and nursing staff.
  • • Ensure proper specimen collection, anticoagulant choice, labeling, and handling for hematology studies.
  • • Maintain and clean laboratory equipment; manage inventory; prepare reagents and controls.
  • • Train, mentor, or supervise laboratory personnel, students, or assistants in hematology procedures.
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Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
Sources & Standards: This site includes information from O*NET by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. Career Clutch has modified some of this information for student readability. USDOL/ETA has not approved, endorsed, or tested these modifications. O*NET® is a trademark of USDOL/ETA.
Last reviewed: Jan 2026
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