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Palliative Care Nurse Practitioner

Nurse Practitioners
Description
Provide specialized palliative care for patients with serious or life-limiting illness, emphasizing symptom relief, quality of life, and goal-concordant care. Practice independently and within an interdisciplinary team across inpatient, outpatient, and home settings. Perform comprehensive assessments; order and interpret targeted tests; and prescribe medications, including controlled substances, as permitted. Lead advance care planning and coordinate transitions among services, including hospice. Must be a registered nurse with graduate education and palliative care expertise.
  • • Conduct comprehensive palliative assessments, including symptom burden and function.
  • • Analyze histories, exams, and diagnostics to set priorities and plans.
  • • Manage pain with multimodal strategies and evidence-based opioid titration.
  • • Treat non-pain symptoms: dyspnea, nausea, constipation, insomnia, anxiety, delirium.
  • • Order and interpret targeted tests for symptom control and medication safety.
  • • Identify and manage adverse effects, interactions, and opioid-related risks.
  • • Develop individualized, goal-concordant care plans with patients and families.
  • • Lead goals-of-care and advance care planning, including code status and POLST.
  • • Educate patients and caregivers on symptom self-management and safe medication use.
  • • Recommend nonpharmacologic interventions such as breathing, relaxation, and positioning.
  • • Prescribe and deprescribe to optimize comfort and reduce polypharmacy.
  • • Determine medication routes and dosing, including breakthrough and taper plans.
  • • Perform comfort-focused procedures within scope, e.g., wound care and drain/catheter management.
  • • Arrange subcutaneous or transdermal delivery systems and bowel regimens as needed.
  • • Schedule and conduct follow-ups to reassess symptoms, function, and goals.
  • • Coordinate care with oncology, hospitalists, primary care, hospice, social work, and chaplaincy.
  • • Refer to specialty services when needs exceed scope, including interventional pain or psychiatry.
  • • Facilitate timely transitions to hospice or other appropriate levels of care.
  • • Advocate for equitable access to palliative resources, home services, and equipment.
  • • Connect families with community resources, respite, and bereavement support.
  • • Document goals-of-care, prognostic estimates, and symptom scores.
  • • Maintain accurate, compliant records and controlled-substance documentation.
  • • Uphold safety, infection control, and secure medication handling policies.
  • • Stay current with palliative guidelines, opioid stewardship, and communication best practices.
  • • Monitor payer requirements for hospice eligibility, DME, and medication coverage.
  • • Maintain knowledge of state and federal rules on NP practice, controlled substances, and directives.
  • • Lead or participate in interdisciplinary team meetings and family conferences.
  • • Support patients and families through terminal emergencies and the active dying phase.
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Source
Tasks & skills: O*NET occupational data (work activities, skills, knowledge). Learn more
Sources & Standards: This site includes information from O*NET by the U.S. Department of Labor, Employment and Training Administration (USDOL/ETA), used under the CC BY 4.0 license. Career Clutch has modified some of this information for student readability. USDOL/ETA has not approved, endorsed, or tested these modifications. O*NET® is a trademark of USDOL/ETA.
Last reviewed: Jan 2026
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